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. 2016 Mar 17;17(4):213–219. doi: 10.1038/gene.2016.12

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Copyright © 2016 Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/

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Venn diagram of overlapping VDR-binding sites in (a) the three myeloid subsets DC1, DC2 and monocyte (CD14) and (b) overlap of the myeloid cell VDR-binding sites with the VDR-binding sites of a hepatic stellate cell line (LX2) and a B-lymphocyte cell line. Overlap of DC2 and DC1 was 91% of DC2 peaks; monocyte and DC1 was 83% of monocyte peaks; DC2 and monocyte was 51% of monocyte peaks; LX2 and myeloid was 19% of LX2 peaks; myeloid and B-lymph was 14% of myeloid peaks; and LX2 and B-lymph was 14% of LX2 peaks. In each case, the cell subset with the largest number of identified VDR peaks is used as the reference to compare overlaps.