Table 2.

Grouped variables entered in multivariate Cox's proportional hazard analysis (Reverse LR Conditional) for disease‐free period after transsphenoidal hypophysectomy resulted in a final model

Grouped Variables Entered	Variables in Final Model	HR	95% CI		P‐Value
ACTH2, ACTH3, ACTH4, ACTH5, Cort1, Cort2, Cort3, Cort4	ACTH3	1.032	0.999	1.066	.060
	ACTH4	0.921	0.845	1.005	.064
	ACTH5	1.055	1.006	1.106	.026*
	Cort1	1.005	1.000	1.010	.041*
	Cort2	0.993	0.986	1.001	.072
	Cort4	1.007	1.002	1.013	.008*
normACTH2, normACTH3, normACTH4, normCort1, normCort2, normCort3, normCort4	normACTH3	2.082	1.237	3.504	.006*
	normCort4	1.805	1.182	2.756	.006*
RI ACTH, RI Cort, RS Cort, AUC Cort	RI ACTH	1.011	0.999	1.022	.067
	RS Cort	1.150	1.064	1.244	<.001*

AUC Cort, area under the curve for cortisol; CI, confidence interval; HR, hazard ratio; normACTH, normalized plasma ACTH concentration to preoperative value; normCort, normalized plasma cortisol concentration to preoperative value; RI, random intercept; RS, random slope.

Significant variables (P < .05) are marked with *.