Table 3.
Results of Cox multivariable analyzes, performed to reflect each of two clinical scenarios. In each, cTnI provided independent predictive value for cardiac death in cats with HCM. The exception was where regional LV hypokinesis was detected by 2D echocardiography
| Multivariable Model | Variable | HR | 95% CI | P‐Value | AIC value |
|---|---|---|---|---|---|
| Model 1: CHF status established, echocardiography unavailable | CHF (yes) | 17.4 | 3.84–78.6 | <.001 | 114.2 |
| cTnI (>0.7 ng/mL) | 6.78 | 1.98–23.2 | .002 | ||
| Model 2.1: CHF status established, echocardiography available | CHF (yes) | 6.35 | 1.10–36.7 | .039 | 111.0 |
| cTnI (>0.7 ng/mL) | 5.61 | 1.61–19.5 | .007 | ||
| LA : Ao (>1.76) | 4.53 | 1.04–19.7 | .044 | ||
| Model 2.2: CHF status established, echocardiography available | CHF (yes) | 11.9 | 2.60–54.4 | .001 | 104.0 |
| Regional LV hypokinesis (yes) | 16.3 | 2.71–97.6 | .002 |
HCM, hypertrophic cardiomyopathy; HR, hazard ratio; 95% CI, 95% confidence intervals; AIC, Aikaike's information criteria; NTproBNP, N‐terminal of pro‐B‐type natriuretic peptide; cTnI, cardiac troponin I; CHF, congestive heart failure; LA : Ao, left atrium to aortic root ratio; LV, left ventricular.