Table 3.

Inputs of the simulation in section “Model comparison and validation with real data”

	EGFR	TNFR	DNA damage
Control	+0.5	+0.5	random value
EGFR inhibitor	–1	+0.5	random value
DNA damage stimuli	random value	+0.5	+1
Both drugs	–1	+0.5	+1

The symbols ‘+’ and ‘–’ represent the perturbation types, i.e., activation and inhibition. The columns are the input nodes of simulation and the rows are various conditions including the treatments of biological experiments with drugs corresponding to wet-lab experiments in [18]