Table 3.
ET A R antagonism with ABT‐627 inhibits cell migration and increases percent residual gap remaining after 24 hours of cell culture
| Condition | Abrams | D17 | HMPOS |
|---|---|---|---|
| Vehicle | 19.5 ± 3.1 | 25.0 ± 2.2 | 28.8 ± 1.9 |
| 10 μM | 40.0 ± 3.9** | 34.5 ± 4.6 | 38.9 ± 3.2 |
| 20 μM | 43.7 ± 3.2** | 47.4 ± 4.3** | 35.3 ± 4.3 |
| 30 μM | 98.7 ± 3.6** | 46.9 ± 3.9** | 51.9 ± 3.9** |
| 40 μM | 94.6 ± 3.0** | 49.3 ± 3.8** | 55.9 ± 5.4** |
Data expressed as mean ± SEM with significance defined as **P < .01.