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. 2016 Feb 3;17(Suppl 2):9. doi: 10.1186/s12863-015-0318-5

Table 1.

Data and trait analysis methods used

First author [ref] Chr Trait source Traits SNP seta Pedigreesb Trait analysis programsb
Transmission Correlation
Bhatnagar [30] All Sim None, HTN No Reduced, complete TDT, PDT, FBAT NA
Darst [41] 3,11 Sim SBP Yes Reduced, complete FBAT MONSTER
Lent [33] 3 None None No Reduced NA NA
Lin [39] All Real HTN Yes Reduced CAPL NA
Papachristou [34] All Sim SBP No Complete NA GEMMA, LMM + Lasso
Saad [32] 3 Sim None, DBP No Complete, augmented MORGAN, IBDstitch NA
Sippy [31] 3 Sim SBP Yes Reduced NA FARVAT
Wang [38] All Sim DBP, SBP, HTN Yes Reduced FBAT NA
Zhou [35] 1,3, 11 Real, sim DBP, SBP No Complete NA MENDEL

All all odd-numbered chromosomes, CAPL combined association in the presence of linkage, Chr chromosome, DBP diastolic blood pressure, FARVAT family-based rare variant association test, FBAT family-based association test, GEMMA genome-wide efficient mixed-model analysis, HTN hypertension, Lasso least absolute shrinkage and selection operator, LMM linear mixed model, Mendel MONSTER minimum p value optimized nuisance parameter score test extended to relatives, NA not applicable, PDT pedigree disequilibrium test, SBP systolic blood pressure, sim simulated, SNP single nucleotide polymorphism, TDT transmission disequilibrium test

aWhether or not a SNP-set approach was used

bSee text