Table 1.
First author [ref] | Chr | Trait source | Traits | SNP seta | Pedigreesb | Trait analysis programsb | |
---|---|---|---|---|---|---|---|
Transmission | Correlation | ||||||
Bhatnagar [30] | All | Sim | None, HTN | No | Reduced, complete | TDT, PDT, FBAT | NA |
Darst [41] | 3,11 | Sim | SBP | Yes | Reduced, complete | FBAT | MONSTER |
Lent [33] | 3 | None | None | No | Reduced | NA | NA |
Lin [39] | All | Real | HTN | Yes | Reduced | CAPL | NA |
Papachristou [34] | All | Sim | SBP | No | Complete | NA | GEMMA, LMM + Lasso |
Saad [32] | 3 | Sim | None, DBP | No | Complete, augmented | MORGAN, IBDstitch | NA |
Sippy [31] | 3 | Sim | SBP | Yes | Reduced | NA | FARVAT |
Wang [38] | All | Sim | DBP, SBP, HTN | Yes | Reduced | FBAT | NA |
Zhou [35] | 1,3, 11 | Real, sim | DBP, SBP | No | Complete | NA | MENDEL |
All all odd-numbered chromosomes, CAPL combined association in the presence of linkage, Chr chromosome, DBP diastolic blood pressure, FARVAT family-based rare variant association test, FBAT family-based association test, GEMMA genome-wide efficient mixed-model analysis, HTN hypertension, Lasso least absolute shrinkage and selection operator, LMM linear mixed model, Mendel MONSTER minimum p value optimized nuisance parameter score test extended to relatives, NA not applicable, PDT pedigree disequilibrium test, SBP systolic blood pressure, sim simulated, SNP single nucleotide polymorphism, TDT transmission disequilibrium test
aWhether or not a SNP-set approach was used
bSee text