Table 1.
Baseline characteristics on admission
| Initial clinical parameters | (N = 66) |
|---|---|
| Age (yr) | 22.1 ± 4.4 |
| Male (%) | 100 |
| Underlying disease: G6PD deficiency (%) | 1.5 |
| Body temperature (°C) | 40.8 ± 2.7 |
| Glasgow coma scale | 7.7 ± 3.5 |
| Median time to achieving BT of <38 °C (hr) | 3.6 (1.8–8.5) |
| Pulse rate (/min) | 132.5 ± 14.7 |
| Mean arterial pressure (mmHg) | 69.4 ± 8.7 |
| Respiratory rate (/min) | 26.2 ± 3.7 |
| Blood tests | |
| Blood urea nitrogen (mg/dL) | 14.1 (4.7–103) |
| Creatinine (mg/dL) | 1.6 (0.9–12.7) |
| Sodium (mEq/L) | 135.2 ± 5.8 |
| Potassium (mEq/L) | 3.4 ± 1.0 |
| Chloride (mEq/L) | 100.6 ± 7.8 |
| Bicarbonate (mEq/L) | 17.25 ± 3.93 |
| Calcium (mg/dL) | 8.3 ± 0.9 |
| Phosphorus (mg/dL) | 1.8 (0.4–14) |
| Magnesium (mg/dL) | 2.0 ± 0.6 |
| CPK (μg/L) | 3671 (162–510680) |
| Glucose (mg/dL) | 98.4 ± 9.3 |
| Aspartate aminotransferase (U/L) | 142.4 ± 61.5 |
| Alanine aminotransferase (U/L) | 96.1 ± 41.5 |
| Alkaline phosphatase (U/L) | 88.2 ± 12.6 |
| Albumin (g/dL) | 3.8 ± 0.3 |
| Total bilirubin (μmol/L) | 1.2 ± 0.4 |
| Positive DIC profile (%) | 42.4 % |
| Urine tests | |
| Urine pH | 5.81 ± 0.78 |
| Urine specific gravity | 1.020 ± 0.01 |
| Urine albumin (range 0–4) | 1.0 (0–3) |
| Urine WBC >5/High power field (%) | 45.4 |
| Urine RBC >5/High power field (%) | 72.7 |
| Urine sodium (mEq/L) | 109 ± 58.95 |
| Urine potassium (mEq/L) | 21.63 ± 21.22 |
| Urine phosphate (mg/dL) | 11.08 ± 9.84 |
| Urine magnesium (mg/dL) | 4.76 ± 6.36 |
Data are expressed as mean ± SD, median (25–75 interquartile), or number (%)
CPK Creatine phosphokinase, G6PD Glucose-6-Phosphate Dehydrogenase