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. 2016 Mar 11;310(10):H1321–H1329. doi: 10.1152/ajpheart.00890.2015

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Fig. 8. — Altered expression of markers in EETs mediated signaling in BCAS rats. A: there was no change in mRNA levels of soluble epoxide hydrolase (sEH) in middle cerebral arteries (MCAs) and PAs after chronic cerebral hypoperfusion. B: however, there was increased expression of sEH in the brain from BCAS rats. C: increased expression of sEH was coupled with increased expression of Cyp2C11 in the brain region around the PAs from BCAS rats. D: mRNA level of TRPV4 was reduced in MCAs and PAs from BCAS rats. *P < 0.05, different from Sham rats.