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. 2016 Mar 24;310(10):G832–G843. doi: 10.1152/ajpgi.00355.2015

Fig. 5.

Fig. 5.

Effects of exercise and/or lack of FGF21 on hepatic phosphorylated cAMP-responsive element-binding protein (CREB) protein content (A), PEPCK mRNA expression to WT-SED (B), PEPCK protein content (C), G6Pase mRNA expression to WT-SED (D), G6Pase protein content (E), pyruvate carboxylase (PC) protein content (F), and hepatic glycogen content (G). Representative Western blots shown in H. Representative images do not reflect the order in which they appear in the graphs. WT, wild-type; FGF21-KO, FGF21 knockout; SED, sedentary; EX, exercise. Values are means ± SE (n = 9–15). #Significant genotype main effect, P ≤ 0.05; *significant exercise main effect, P ≤ 0.05; †significant differences vs. WT-SED and FGF21KO-EX, P ≤ 0.05; Δsignificant differences vs. WT-SED, P ≤ 0.05. A.U., arbitrary units.