Table 2.

Serum measures

Variable	WT-SED	WT-EX	FGF21KO-SED	FGF21KO-EX
FGF21, pg/ml	892.50 ± 199.63	858.60 ± 130.97	BDL	BDL
Insulin, ng/ml	1.23 ± 0.10	0.82 ± 0.08†	2.61 ± 0.29*	1.95 ± 0.23†*
Glucose, mg/dl	280.20 ± 10.75	280.53 ± 15.77	332.22 ± 21.89*	350.84 ± 13.21*
β-Hydroxybutyrate, μmol/l	41.64 ± 4.29‡	28.04 ± 2.69†	27.12 ± 2.38*	24.04 ± 2.13†*
Adiponectin, μg/ml	21.38 ± 1.05	18.10 ± 0.64†	20.17 ± 0.92	17.85 ± 0.49†
TG, mg/dl	61.06 ± 4.69	47.33 ± 2.10†	64.44 ± 3.91	57.89 ± 2.53†
Cholesterol, mg/dl	95.37 ± 4.96	91.42 ± 1.90	111.51 ± 4.28*	99.10 ± 4.28*
FFA, μM	769.44 ± 53.55	598.89 ± 32.73†	813.11 ± 26.14	680.22 ± 35.05†

Values are means ± SE (n = 9–15).

^*Significant genotype main effect (P ≤ 0.05);

^†significant exercise main effect (P ≤ 0.05);

^‡significant differences vs.

WT-EX and FGF21KO-SED (P ≤ 0.05). BDL, below detectable limits; TG, triglyceride; FFA, free fatty acid.