. 2016 Jun 6;16:246. doi: 10.1186/s12879-016-1578-z

Table 3.

Test performance and agreement of diagnostic modalities

	Culture as reference standard					Cytology as reference standard					Composite reference standard: culture and/or cytology
	Sensitivity^a		Specificity^a		Cohen’s Kappa	Sensitivity^a		Specificity^a		Cohen’s Kappa	Sensitivity^a		Specificity^a		Cohen’s Kappa
	n/N		n/N		k	n/N		n/N		k	n/N		n/N		k
Cytology	6/9	67 %	22/24	92 %	0.60	-	-	-	-	-	-	-	-	-	-
Culture	-	-	-	-	-	6/8	75 %	22/25	88 %	0.60	-	-	-	-	-
ZN	1/9	11 %	24/25	96 %	0.10	3/18	17 %	43/43	100 %	0.22	3/21	14 %	41/41	100 %	0.18
Xpert	5/9	56 %	26/27	96 %	0.58	11/16	69 %	38/41	93 %	0.64	11/19	58 %	40/43	93 %	0.55
EasyNAT	2/9	22 %	30/30	100 %	0.31	4/18	22 %	43/43	100 %	0.29	4/21	19 %	46/46	100 %	0.24
Any diagnostic modality	6/9	67 %	28/30	93 %	0.62	18/18	100 %	40/43	93 %	0.89	13/21	62 %	38/41	93 %	0.58

^aCalculated only for patients without missing data