Table 2.
Bivariate logistic regression predicting internalizing problems at age 3
| Odds Ratio | 95.0 % CI for OR | p-value | |
|---|---|---|---|
| Internalizing ≥ 90th percentile | |||
| BDNF Val66Met | |||
| Val/Met compared to Val/Val | 1.088 | 0.674–1.757 | 0.730 |
| Met/Met compared to Val/Val | 0.712 | 0.166–3.058 | 0.648 |
| EPDS | 3.838 | 2.254–6.535 | <0.001 |
| Life events | 3.321 | 1.716–6.425 | <0.001 |
| LSS | 2.394 | 1.199–4.779 | 0.013 |
| Parental unemployment | 2.749 | 1.566–4.828 | <0.001 |
| Parental immigration status | 3.084 | 1.778–5.350 | <0.001 |
| Anxious depressed ≥ 90th percentile | |||
| BDNF Val66Met | |||
| Val/Met compared to Val/Val | 1.886 | 1.069–3.326 | 0.028 |
| Met/Met compared to Val/Val | 0.707 | 0.093–5.370 | 0.738 |
| EPDS | 3.048 | 1.569–5.920 | 0.001 |
| Life events | 4.076 | 1.934–8.587 | <0.001 |
| LSS | 3.270 | 1.518–7.046 | 0.002 |
| Parental unemployment | 2.610 | 1.313–5.188 | 0.006 |
| Parental immigration status | 3.835 | 2.025–7.263 | <0.001 |
| Withdrawn ≥ 90th percentile | |||
| BDNF Val66Met | |||
| Val/Met compared to Val/Val | 0.776 | 0.421–1.430 | 0.416 |
| Met/Met compared to Val/Val | 1.536 | 0.449–5.256 | 0.494 |
| EPDS | 3.212 | 1.816–6.410 | <0.001 |
| Life events | 3.704 | 1.768–7.763 | 0.001 |
| LSS | 2.095 | 0.910–4.826 | 0.082 |
| Parental unemployment | 2.549 | 1.316–4.935 | 0.006 |
| Parental immigration status | 3.716 | 2.003–6.895 | <0.001 |
CI confidence interval, OR odds ratio, BDNF brain derived neurotrophic factor, EPDS Edinburgh postnatal depression scale, LSS life stress score, CBCL child behaviour checklist. Results concerning Apgar score, Small for Gestational Age (SGA), smoking during pregnancy, birthweight, duration of gestation, neonatal illness, non-optimal pregnancy/birth, sex and 5-HTTLPR were not statistically significant and are not shown
Logistic regression. Dependent variables: CBCL (internalizing, withdrawn and anxious depressed). Independent variables (0 is used as a reference level): EPDS (0 ≤ 9, 1 ≥ 10), Life Events and LSS (0 < 90th percentile, 1 ≥ 90th percentile), Parental unemployment (0 = both parents employed, 1 = one or both parents unemployed), Parental immigration status (0 = both parents born in Sweden, 1 = one or both parents born abroad)