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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: Clin Cancer Res. 2016 Jun 1;22(11):2668–2674. doi: 10.1158/1078-0432.CCR-15-2429

Fig. 2. T2, RSI-MRI, Gleason grade, and H&E: Cases 2, 5, 6, and 10.

Fig. 2

A) T2-weighted MR images, after in-plane affine transformation to correspond to the histopathology slides, B) RSI-MRI color coded cellularity maps, C) “Digital prostate map” grid overlay color-coded for RSI-MRI cellularity index, D) “Digital prostate map” grid overlay color-coded for Gleason grade, E) H&E-stained WM histopathological prostate section with tumor area(s) outlined, F) Plots for each case of the mean RSI-MRI signal corresponding to each histological Gleason grade based on voxel-level analysis. Error bars represent the standard errors of the mean. Blue outline in A&B indicates the correspondence of the histopathology slide to the MR image. Abbreviations: H&E, haematoxylin & eosin; MR, magnetic resonance; RSI, restriction spectrum imaging; WM, whole mount.