Effects of voluntary wheel running on distance run (A), food intake (B), body mass (C), blood glucose during a GTT (D), epididymal adipose tissue mass (E), and protein content of PEPCK and G6Pase (F). Values are pooled from 6- and 12-h experiments, unless indicated. Two-way ANOVA main effect for VWR, §P < 0.05. #P < 0.05, main effect of time. Unpaired t-test between sedentary (SED) and voluntary wheel running (VWR) rats, *P < 0.05.