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Effect of voluntary wheel running on 12-h exposure to LPS for mRNA expression of TNF-α (A), IL-6 (B), IL-1β (C), Ccl2 (D), Nos2 (E), and IL-10 (F). Text indicates P values for two-way ANOVA, and when an interaction was observed, †P < 0.05 indicates LPS group significantly different within SED or VWR and ‡P < 0.05 indicates VWR group different within Sal or LPS. Inset: fold change relative to SAL control and *P < 0.05 for t-test between SED and VWR groups.
