Table 1. P-values of the gene-based association tests for the DMN with the ADNI-1 data.
GEE | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Gene region | No. SNPs | Chr | Position | Score | aSPUset | aSPUset-Score | MANOVA | MDMR | KMR | MFLM | |
AMOTL1 | 6 | 11 | 94,121,155 | 94,269,566 | 1.18e0-4 | 1.0e-08 | 1.0e-08 | 7.73e-05 | 3.48e-07 | 0.451 | 7.73e-05 |
APOC1 | 4 | 19 | 50,089,760 | 50,134,446 | 6.14e-04 | 1.0e-08 | 1.0e-08 | 3.45e-04 | 4.42e-08 | 0.342 | 2.30e-04 |
APOE | 6 | 19 | 50,080,878 | 50,124,490 | 1.27e-03 | 1.0e-08 | 1.0e-08 | 7.93e-04 | 2.21e-07 | 0.268 | 5.97e-04 |
TOMM40 | 10 | 19 | 50,066,316 | 50,118,786 | 0.023 | 1.0e-08 | 1.0e-08 | 1.86e-02 | 6.99e-06 | 0.569 | 1.04e-03 |
Chr, chromosome.