Table 2.

Reported phosphorylation sites of connexins, responsible kinases and the effect on hemichannels

Kinases	Connexins	Phosphorylated residues	Reported effects on HCs	References
PKA	Cx35/36	n/a	reduced HC permeability	[89, 90]
AKT (PKB)	Cx43	Ser369, Ser373	increased HC permeability	[85, 88]
	Cx26	n/a	increased HC permeability	[92]
PKC	Cx43	Ser368	reduced HC permeability	[47, 83, 84, 86, 93]
MAPK	Cx43	serines 255, 262, 279, 282	reduced HC permeability	[54, 74, 87]