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. 2016 May 24;17(Suppl 1):14. doi: 10.1186/s12860-016-0090-z

Fig. 1.

Fig. 1

Interactions between glutamatergic and electrical synapses that leads to activity-dependent potentiation of electrical transmission. a At goldfish mixed synapses the activity of co-existing glutamatergic synapses leads to activation of NMDARs which initiates changes in electrical (and chemical) transmission [the second form of activity-dependent potantiation involvimg mGluRs, endocannabinoids and dopamine is not represented]. b, At mammals, activation of mGluRs or NMDARs, including extrasynaptic NMDARs (eNMDAR), leads to changes in electrical transmission