Table 2. Effect of fibrin clot, TNF-α and skin cells on wound healing.
Fibroblasts | Wound | Fibrin | TNF-α | Keratinocytes | Result |
---|---|---|---|---|---|
- | - | - | - | - | Normal DED |
- | - | + | - | - | Normal DED |
- | + | - | - | - | Open wide wound (Fig 3A) |
- | + | + | - | - | Narrowed wound (Fig 3B) |
+ | - | - | - | - | Normal Dermis + F |
+ | - | + | - | - | Normal Dermis + F |
+ | + | - | - | - | Healed (Fig 3C) |
+ | + | + | - | - | Narrowed wound (Fig 3D) |
+ | + | - | - | + | Open wide wound (Fig 3E, 3F and 3G) |
+ | + | + | + | + | Epidermis healed, healed wound (Fig 3H) |
+ | + | + | + | + | Epidermis healed, narrowed wound (Fig 3I) |
Fibrin = Fibrin Clots, TNF = 300U/ml TNF-α, F = Fibroblasts.