Table 2. Effects of compound 1 on renal function test in rats.
Dose | Sodium (mmol/L) | Potassium (mmol/L) | Chloride (mmol/L) | CO2 (mmol/L) | Anion gap (mmol/L) | Urea (mmol/L) | Creatinine (μmol/L) |
---|---|---|---|---|---|---|---|
Vehicle | 141.53 ± 0.42 | 4.65 ± 0.11 | 105.63 ± 0.98 | 23.05 ± 0.44 | 18.50 ± 0.25 | 7.71 ± 0.33 | 41.280 ± 2.88 |
(500mg/kg) | 143.01 ± 0.69 | 4.55 ± 0.13 | 103.38 ± 0.85 | 22.84 ± 0.42 | 17.38 ± 0.30 | 7.97 ± 0.28 | 43.09 ± 4.17 |
Values expressed as mean ± S.E.M. There are no significant differences between groups. Significant value at p<0.05.