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. 2016 Jun 7;11(6):e0156896. doi: 10.1371/journal.pone.0156896

Fig 3. Cytotoxic response against AURKA-positive GANMO-1 cells.

Fig 3

(A) Total cell killing of Chromium-labelled GANMO-1 cells was assessed by Chromium release after 3 hours co-culture with NGM, coAUK, or siAUK effector cells. (B) Effector cells were co-cultured (E:T = 2:1) for 3 hours with a range of HLA A*0201+ target cells in the presence of CD107a antibody (C1R-A2 is an AURKA-negative control). CD107a degranulation was assessed by flow cytometry (* p<0.05, One-way ANOVA with Tukey’s test, n = 3, ± S.D.).