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. 2016 Jun 7;11(6):e0156980. doi: 10.1371/journal.pone.0156980

Fig 4. Summary of relative expression for imprinted genes on Chromosome 15 and Chromosome 11 in individual blastocysts.

Fig 4

A) Relative gene expression of SNRPN and UBE3A in control blastocysts (n = 10) compared to trisomy 15 (n = 10) and monosomy 15 (n = 10) blastocysts. B) Relative gene expression of H19, KCNQ1OT1 and CDKN1C in control blastocysts (n = 10) compared to trisomy 11 (n = 10) and monosomy 11 (n = 10) blastocysts. Relative expression between control and aneuploid groups was normalized to the housekeeping gene PPIA (7p13) using the Relative Expression Software Tool (REST) to determine an expression ratio that was tested for significance by a Pair Wise Fixed Reallocation Randomization Test. Differences were considered to be statistically significant when p<0.05, Star “*” denotes statistical significance.