Table 4. Results for the lower limit of quantitation.
Sample iD | Dilution factor* |
Observed Titers (IU/mL) | Observed median titer (IU/mL) | Percent of the results within ± 2-fold of the median (%) |
||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Titer 1 |
Titer 2 |
Titer 3 |
Titer 4 |
Titer 5 |
Titer 6 |
Titer 7 |
Titer 8 |
Titer 9 |
Titer 10 |
Titer 11 |
||||
HRIG | 1000 | 0.12 | 0.09 | 0.1 | 0.2 | 0.3 | 0.2 | 0.12 | 0.2 | 0.12 | 0.2 | 0.2 | 0.2 | 100 |
500 | 0.22 | 0.3 | 0.4 | 0.3 | 0.3 | 0.22 | 0.24 | 0.3 | 0.3 | 0.2 | 0.2 | 0.3 | 73 | |
100 | 1.2 | 1.4 | 1.0 | 1.4 | 1.4 | 0.9 | 1.2 | 1.3 | 1.2 | 1.2 | 0.8 | 1.2 | 100 | |
50 | 2.4 | 2.0 | 2.8 | 2.0 | 1.8 | 2.4 | 1.9 | 2.4 | 2.2 | 2.4 | 2.3 | 2.35 | 100 | |
25 | 4.8 | 4.5 | 4.8 | 4.0 | 4.6 | 4.5 | 4.2 | 3.8 | 4.2 | 4.6 | 4.8 | 4.55 | 100 | |
10 | 12.5 | 14.5 | 10.5 | 11.4 | 12.5 | 10.5 | 12.5 | 12.8 | 10.5 | 12.5 | 10.7 | 11.95 1111.211.2 |
100 | |
5 | 0.4 | 0.6 | 0.4 | 0.4 | 0.4 | 0.4 | 0.3 | 0.4 | 0.3 | 0.5 | 0.4 | 0.4 | 100 |
N/A, Not Applicable. *Samples were pre-diluted in rabies antibody negative human serum to the desired dilution factor before testing