Table 2.
Clinical characteristics of patients with versus without epilepsy before surgery
Epilepsy before Surgery |
P | ||
---|---|---|---|
Yes | No | ||
N = 244 (31.3%) | N = 535 (68.7%) | ||
Age at diagnosis, y | |||
Median | 56 | 58 | .265 |
Range | 18–88 | 19–87 | |
Sex, N (%) | |||
Male | 85 (34.8) | 162 (30.3) | .214 |
Female | 159 (65.2) | 373 (69.7) | |
WHO grade, N (%) | |||
I | 200 (82.0) | 438 (81.9) | .765 |
II | 38 (15.6) | 81 (15.1) | |
III | 6 (2.5) | 16 (3) | |
Locationa, N (%) | |||
Convexity | 77 (35.9) | 90 (19.1) | <.001 |
Parasagittal | 39 (18.7) | 92 (20.7) | .555 |
Skull base | 81 (38.8) | 179 (40.2)1 | .733 |
Posterior fossa | 9 (4.3) | 72 (16.2) | <.001 |
Other | 5 (1.9) | 17 (3.8) | .347 |
Maximal diameterb, mm | |||
Median | 42 | 40 | .088 |
Range | 11–89 | 12–100 | |
Simpson gradec, N (%) | |||
1 | 51 (35.9) | 92 (28.2) | .295 |
2 | 57 (40.1) | 162 (49.7) | |
3 | 15 (10.6) | 26 (8.0) | |
4 | 15 (10.6) | 39 (12.0) | |
5 | 4 (2.8) | 7 (2.1) | |
Multiple meningiomas, N (%) | |||
Yes | 35 (14.3) | 90 (16.8) | .402 |
No | 209 (85.7) | 445 (83.2) | |
Neurological deficit before surgeryd, N (%) | |||
Yes | 104 (42.6) | 275 (51.4) | .023 |
No | 140 (57.4) | 269 (48.6) | |
Outcome of neurological deficits after surgery, N (%) | |||
Recovered | 57 (54.8) | 82 (29.8) | <.001 |
Residual deficit | 19 (18.3) | 105 (38.2) | |
Not improved | 28 (26.9) | 88 (32.0) | |
Epileptiform EEG potentialsf, N (%) | |||
Yes | 25 (21.9) | 15 (10.8) | .016 |
No | 89 (78.1) | 124 (89.2) | |
Tumor progression, N (%) | |||
Yes | 51 (20.9) | 152 (28.4) | .027 |
No | 193 (79.1) | 383 (71.6) |
aN = 661, not including patients with multiple meningiomas.
bDocumentation available for 694 patients (CT/MRI = 631/63).
cDocumentation available for 468 patients.
dNot including headache and seizures.
ePatients with perioperative-onset neurologic deficits and a minimum follow-up of 1 year (N = 338).
fDocumentation of preoperative EEG recordings available for 253 patients.