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. 2015 Dec 18;18(7):1002–1010. doi: 10.1093/neuonc/nov303

Table 2.

Clinical characteristics of patients with versus without epilepsy before surgery

Epilepsy before Surgery
P
Yes No
N = 244 (31.3%) N = 535 (68.7%)
Age at diagnosis, y
 Median 56 58 .265
 Range 18–88 19–87
Sex, N (%)
 Male 85 (34.8) 162 (30.3) .214
 Female 159 (65.2) 373 (69.7)
WHO grade, N (%)
 I 200 (82.0) 438 (81.9) .765
 II 38 (15.6) 81 (15.1)
 III 6 (2.5) 16 (3)
Locationa, N (%)
 Convexity 77 (35.9) 90 (19.1) <.001
 Parasagittal 39 (18.7) 92 (20.7) .555
 Skull base 81 (38.8) 179 (40.2)1 .733
 Posterior fossa 9 (4.3) 72 (16.2) <.001
 Other 5 (1.9) 17 (3.8) .347
Maximal diameterb, mm
 Median 42 40 .088
 Range 11–89 12–100
Simpson gradec, N (%)
 1 51 (35.9) 92 (28.2) .295
 2 57 (40.1) 162 (49.7)
 3 15 (10.6) 26 (8.0)
 4 15 (10.6) 39 (12.0)
 5 4 (2.8) 7 (2.1)
Multiple meningiomas, N (%)
 Yes 35 (14.3) 90 (16.8) .402
 No 209 (85.7) 445 (83.2)
Neurological deficit before surgeryd, N (%)
 Yes 104 (42.6) 275 (51.4) .023
 No 140 (57.4) 269 (48.6)
Outcome of neurological deficits after surgery, N (%)
 Recovered 57 (54.8) 82 (29.8) <.001
 Residual deficit 19 (18.3) 105 (38.2)
 Not improved 28 (26.9) 88 (32.0)
Epileptiform EEG potentialsf, N (%)
 Yes 25 (21.9) 15 (10.8) .016
 No 89 (78.1) 124 (89.2)
Tumor progression, N (%)
 Yes 51 (20.9) 152 (28.4) .027
 No 193 (79.1) 383 (71.6)

aN = 661, not including patients with multiple meningiomas.

bDocumentation available for 694 patients (CT/MRI = 631/63).

cDocumentation available for 468 patients.

dNot including headache and seizures.

ePatients with perioperative-onset neurologic deficits and a minimum follow-up of 1 year (N = 338).

fDocumentation of preoperative EEG recordings available for 253 patients.