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(A). EFS-induced vasoconstriction in endothelium-denuded mesenteric segments from four- (4W) and eight-week (8W) diabetic and non-diabetic rats. Effect of L-NAME on the vasoconstrictor responses induced by EFS in mesenteric segments from control (B), four- (C) and eight-week diabetic (D) rats. Results (mean ± SEM) are expressed as a percentage of the initial contraction elicited by KCl. N = 5–7 animals per group.
