Table 1.

Survey of Substrates for Pd/RuPhos Catalyzed Cross-Coupling of Alkylboronates and Bromobenzene.^a

^aDeprotection for 2 h at rt, followed by solvent removal and cross-coupling for 12 h at 70 °C.

^bYield determined by ¹H NMR versus 1,3,5-trimethoxybenzene as an internal standard.

^cThe substrate was prepared by Cs₂CO₃-catalyzed diboration in THF/methanol and the solvent evaporated prior to subjection to cross-coupling.