Table 2.
and of dopamine receptor-mediated signaling pathway components
| σ = 50,000 | σ = 100,000 | σ = 150,000 | ||||
| Component | ||||||
| ADCY2 | 0.238 | 0.347 | 0.268 | 0.169 | 0.282 | 0.089* |
| CDK5 | 0.224 | 0.377 | 0.132 | 0.707 | 0.158 | 0.683 |
| COMT | 0.456 | 0.055* | 0.355 | 0.087* | 0.358 | 0.049* |
| DBH | 0.171 | 0.468 | 0.216 | 0.460 | 0.258 | 0.319 |
| DRD1 | 0.241 | 0.384 | 0.291 | 0.225 | 0.315 | 0.123 |
| GNAI2 | 0.073 | 0.791 | 0.185 | 0.562 | 0.244 | 0.363 |
| GNAI3 | 0.449 | 0.127 | 0.429 | 0.127 | 0.389 | 0.153 |
| GNAZ | 0.277 | 0.295 | 0.220 | 0.451 | 0.169 | 0.759 |
| GNB3 | 0.450 | 0.108 | 0.370 | 0.131 | 0.272 | 0.262 |
| PPP1CC | 0.660 | 0.074* | 0.641 | 0.054* | 0.525 | 0.009* |
| PPP1R1B | 0.392 | 0.124 | 0.374 | 0.109 | 0.350 | 0.125 |
| SLC6A3 | 0.646 | 0.078* | 0.554 | 0.086* | 0.463 | 0.076* |
| SNAP25 | 0.158 | 0.633 | 0.141 | 0.760 | 0.134 | 0.868 |
| VAMP1 | −0.009 | 0.931 | −0.009 | 0.924 | 0.058 | 0.900 |
| VAMP2 | 0.331 | 0.149 | 0.292 | 0.196 | 0.280 | 0.199 |
| VAMP3 | 0.194 | 0.530 | 0.233 | 0.393 | 0.270 | 0.242 |
| VAMP8 | — | — | 0.322 | 0.166 | 0.355 | 0.063* |
Variance of the Gaussian kernel used for smoothing point estimates is shown by σ. Dashes indicate insufficient SNPs present for smoothing.
Genes with , those genes in regions with bootstrapped in the top 10% of all genes’ regions.