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. 2016 May 2;113(22):6178–6181. doi: 10.1073/pnas.1525530113

Table 2.

FST and PFST of dopamine receptor-mediated signaling pathway components

σ = 50,000 σ = 100,000 σ = 150,000
Component FST PFST FST PFST FST PFST
ADCY2 0.238 0.347 0.268 0.169 0.282 0.089*
CDK5 0.224 0.377 0.132 0.707 0.158 0.683
COMT 0.456 0.055* 0.355 0.087* 0.358 0.049*
DBH 0.171 0.468 0.216 0.460 0.258 0.319
DRD1 0.241 0.384 0.291 0.225 0.315 0.123
GNAI2 0.073 0.791 0.185 0.562 0.244 0.363
GNAI3 0.449 0.127 0.429 0.127 0.389 0.153
GNAZ 0.277 0.295 0.220 0.451 0.169 0.759
GNB3 0.450 0.108 0.370 0.131 0.272 0.262
PPP1CC 0.660 0.074* 0.641 0.054* 0.525 0.009*
PPP1R1B 0.392 0.124 0.374 0.109 0.350 0.125
SLC6A3 0.646 0.078* 0.554 0.086* 0.463 0.076*
SNAP25 0.158 0.633 0.141 0.760 0.134 0.868
VAMP1 −0.009 0.931 −0.009 0.924 0.058 0.900
VAMP2 0.331 0.149 0.292 0.196 0.280 0.199
VAMP3 0.194 0.530 0.233 0.393 0.270 0.242
VAMP8 0.322 0.166 0.355 0.063*

Variance of the Gaussian kernel used for smoothing point estimates is shown by σ. Dashes indicate insufficient SNPs present for smoothing.

*

Genes with PFST<0.1, those genes in regions with bootstrapped FST in the top 10% of all genes’ regions.