Fig. 1.
Crystal structure of the DBP-II/2D10scFv complex. (A) Overall structure of the DBP-II/2D10scFv complex shown in ribbon representation. The DBP-II domain is colored in green. The scFv heavy chain (VH) is in blue, and the light chain (VL) is in orange. (B) Ribbon representation of DBP-II mapping the 2D10 epitopes. Residues contacted by the scFv are shown in stick form. Residues contacted by the heavy chain are colored blue, residues contacted by the light chain are in orange, and residues contacted by both are in beige. Residues not contacted by mAb are in green. Regions of disorder are shown as a dotted line. (C) Surface representation of the DBP-II. Color scheme is as in B.