Table 3. Annualized change in weight (kg/y) during visit intervals in Phase 2 and 3a.
Time interval | |||||||
---|---|---|---|---|---|---|---|
|
|||||||
Baseline to 6 m | 6 m to 12 m | 12 m to 18 m | 18 m to 24 m | 24 m to 30 m | 30 m to 42 m | 42 m to 60 m | |
All | 0.49 [0.45 to 0.54] | 0.50 [0.46 to 0.55] | 0.38 [0.34 to 0.43] | 0.14 [0.11 to 0.18] | 0.10 [0.08 to 0.13] | 0.06 [0.04 to 0.09] | 0.01 [0.00 to 0.03] |
SD | 0.68 [0.62 to 0.74] | 0.59 [0.53 to 0.65] | 0.56 [0.50 to 0.62] | 0.09 [0.06 to 0.14] | −0.02 [−0.01 to 0.05] | 0.02 [0.01 to 0.05] | 0.02 [0.01 to 0.05] |
PC | 0.29 [0.23 to 0.35] | 0.41 [0.35 to 0.48] | 0.21 [0.16 to 0.27] | 0.20 [0.15 to 0.26] | 0.22 [0.17 to 0.28] | 0.10 [0.07 to 0.15] | 0.00 [0.00 to 0.02] |
P-valueb | 0.0004 | 0.10 | 0.26 | 0.37 | 0.044 | 0.15 | 0.45 |
Data limited to 491 participants (less the four who subsequently died) from the Baltimore, Durham, and Baton Rouge clinical centers who were initially enrolled in either the SD or PC interventions for the Weight Loss Maintenance Trial.
P-value for comparison of slope of PC and slope of SD adjusting for site, age, race, gender, race-gender interaction, and starting weight.
SD = self-directed; PC = personal contact; [95% CI].