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. 2014 Jun 17;10(8):2255–2266. doi: 10.4161/hv.29511

Table 5. PPPM cost differences of first RV episodes relative to their matched control episodes in commercially insured and Medicaid populations, overall and stratified by age and pre/post-RV vaccine availability.

PPPM cost differences (incremental cost of RV episodes)12
  Commercial Medicaid
  Mean (95% CI) Mean (95% CI)
     Overall $3363 ($3308–$3418) $1831 ($1768–$1887)
  Hospitalizations $2484 ($2429–$2541) $1374 ($1318–$1426)
  Outpatient visits $416 ($397–$434) $166 ($158–$174)
  ER visits $430 ($414–$445) $214 ($205–$224)
  Pharmacy $34 ($30–$37) $76 ($67–$85)
Age
<1 y
     Pre1 $3368 ($3191–$3523) $1712 ($1629–$1806)
     Post1 $2992 ($2782–$3216) $2266 ($1884–$2629)
0 to <2 mo
       Pre1 $3839 ($3080–$4607) $2448 ($1986–$2938)
       Post1 $3355 ($2735–$4008) $2769 ($1348–$3882)
2 to <4 mo
       Pre1 $3153 ($2550–$3697) $1818 ($1539–$2099)
       Post1 $2703 ($2051–$3407) $2083 ($1339–$2738)
4 to <6 mo
       Pre1 $3717 ($3235–$4201) $1819 ($1587–$2100)
       Post1 $2623 ($2074–$3216) $3112 ($1973–$4494)
6 to <12 mo
       Pre1 $3266 ($3072–$3449) $1556 ($1463–$1666)
       Post1 $3045 ($2791–$3324) $1911 ($1544–$2301)
1 to <2 y
     Pre1 $3416 ($3299–$3517) $1774 ($1700–$1861)
     Post1 $3427 ($3295–$3581) $2146 ($1813–$2532)
2 to <5 y
     Pre1 $3401 ($3267–$3525) $1838 ($1713–$1970)
     Post1 $3768 ($3617–$3919) $2298 ($1921–$2727)

Notes: CI, confidence interval; PPPM, per-patient per-month; RV, rotavirus; SD, standard deviation. Costs are in 2010 USD.1Pre- and post-RV vaccine availability periods were defined the time through January 1, 2007 and the time after that date, respectively; 2The incremental cost analysis tests the null hypothesis of cost difference equal to $0 between RV and control episodes.