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Figure 7. HCV-specific memory T cells persist in circulation. At the final timepoint of the study, 6 wk PIR, cytokine-secreting and putative cytolytic (surface-CD107a+/GrzB+) memory-like CD8+ T cells remained detectable in the blood, as compared with baseline samples, in response to HCV-peptide stimulation. Memory-like CD8+ T cells were characterized as effector (EM; CD45RA-/CD27-) or central (CM; CD45RA-/CD27+) memory phenotypes.
