Table 1. Proposed mechanisms of OIT.

Proposed mechanisms of OIT
Reduced activation of basophils and mast cells
Generation of IgG4 blocking antibody
Decrease in IgE synthesis
T cell anergy
Depletion of specific Th2 Cells
Re-education of specific Th2 cells with switch to Th1 or Tr1
Induction of regulatory T cells
Induction of regulatory B cells
Induction of tolerogenic dendritic cells