TABLE 2.
MIC distribution (μg/mL) of dapsone against Gram-negative and Gram-positive pathogens isolated from the CANWARD Study 2014
| ORGANISM (NO. STRAINS TESTED) | ≤ 0.5 | 1 | 2 | 4 | 8 | 16 | 32 | 64 | 128 | 256 | 512 | > 512 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Escherichia coli (100) | 1 | 10 | 80 | 100 | ||||||||
| Klebsiella pneumonia (30) | 3.3 | 63.3 | 100 | |||||||||
| Enterobacter cloacae (30) | 16.7 | 73.3 | 100 | |||||||||
| Proteus mirabilis (30) | 33.3 | 73.3 | 100 | |||||||||
| Klebsiella oxytoca (20) | 10 | 65 | 100 | |||||||||
| Serratia marcescens (20) | 15 | 100 | ||||||||||
| Stenotrophomonas maltophilia (10) | 10 | 50 | 60 | 100 | ||||||||
| Pseudomonas aeruginosa (50) | 2 | 6 | 22 | 100 | ||||||||
| Staphylococcus aureus, MSSA (50) | 16 | 46 | 90 | 100 | ||||||||
| Staphylococcus aureus, MRSA (50) | 2 | 10 | 46 | 80 | 96 | 100 | ||||||
| Enterococcus faecalis (30) | 1.33 | 6.7 | 10 | 26.7 | 46.7 | 70 | 93.3 | 100 | ||||
| Enterococcus faecium (17) | 5.9 | 41.2 | 88.2 | 100 | ||||||||
| Staphylococcus epidermidis (48) | 10.4 | 39.6 | 66.7 | 89.6 | 97.9 | 100 | ||||||
| Streptococcus agalactiae (10) | 30 | 60 | 80 | 100 | ||||||||
| Streptococcus pyogenes (29) | 3.4 | 17.2 | 34.5 | 55.2 | 62.1 | 82.8 | 86.2 | 93.1 | 100 |