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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Crit Care Med. 2016 Jul;44(7):e492–e501. doi: 10.1097/CCM.0000000000001472

Figure 2. Neutrophil transwell migration during AKI.

Figure 2

Rhabdomyolysis-induced AKI causes impaired neutrophil transwell migration as early as 4h after induction (A, n=7–8), lasting at least as long as 24h (B, n=6–9). Nephrotoxic AKI (n=6) significantly inhibits neutrophil transwell migration 24h after induction (B). Incubation in normal serum completely restores normal neutrophil transwell migration in rhabdomyolysis-induced AKI (n=8–10) but only incompletely and nephrotoxic AKI (n=8) (C). Normal neutrophil transwell migration is completely restored in both nephrotoxic AKI (n=6) and rhabdomyolysis-induced AKI (n=8–10) after incubation in MEM buffer (D).