Table 1.
Effect of Pũrṇa Cantirotaya Centũram on hematological parameters.
| Parameters | Control (honey) | Low dose (2.5 mg/kg b.w.) | Mid dose (25 mg/kg b.w.) | High dose (50 mg/kg b.w.) |
|---|---|---|---|---|
| WBC (×109/L) | 8.06 ± 5.06 | 5.26 ± 4.11 | 6.87 ± 4.68 | 7.48 ± 6.19 |
| Lymph [%] | 62.13 ± 11.72 | 61.89 ± 20.71 | 56.05 ± 7.99 | 60.22 ± 5.43 |
| Mon [%] | 4.30 ± 1.79 | 3.42 ± 1.38 | 3.66 ± 0.35 | 4.46 ± 1.52 |
| Gran [%] | 34.32 ± 9.79 | 34.69 ± 19.48 | 40.29 ± 7.99 | 35.32 ± 3.97 |
| RBC (×1012/L) | 7.16 ± 3.58 | 5.29 ± 3.57 | 6.70 ± 3.06 | 7.76 ± 3.66 |
| HGB (g/dL) | 12.11 ± 6.03 | 8.90 ± 6.09 | 11.27 ± 5.77 | 12.45 ± 5.84 |
| HCT [%] | 35.02 ± 18.06 | 26.36 ± 18.17 | 31.00 ± 14.24 | 37.33 ± 17.54 |
| MCV (fL) | 51.66 ± 5.99 | 49.97 ± 3.42 | 48.52 ± 2.69 | 49.07 ± 1.64 |
| MCH (pg) | 17.82 ± 2.90 | 16.68 ± 1.26 | 16.38 ± 1.05 | 16.27 ± 0.58 |
| MCHC (g/dL) | 34.67 ± 2.63 | 33.55 ± 1.57 | 30.57 ± 10.74 | 33.27 ± 0.57 |
| RDW [%] | 13.05 ± 3.81 | 11.44 ± 0.89 | 11.650 ± 1.23 | 11.43 ± 0.94 |
| PLT (×109/L) | 200.70 ± 78.19 | 210.9 ± 55.6 | 227.5 ± 55.95 | 196.50 ± 144.17 |
| MPV (fL) | 6.53 ± 0.62 | 6.76 ± 1.03 | 6.38 ± 0.76 | 6.50 ± 0.64 |
| PDW | 15.30 ± 0.47 | 15.74 ± 0.89 | 15.45 ± 0.55 | 15.130 ± 0.46 |
| PCT [%] | 0.131 ± 0.04 | 0.130 ± 0.03 | 0.142 ± 0.035 | 0.130 ± 0.10 |
Comparison was made between vehicle control and test groups using the one-way ANOVA test followed by Dunnett's test. Values are mean ± SD for 10 rats in each group (P ≤ 0.05).
RBC: red blood corpuscles; HGB: hemoglobin; HCT: hematocrit; MCV: mean corpuscular volume; MCH: mean corpuscular hemoglobin; MCHC: mean corpuscular hemoglobin concentration; WBC: white blood cells; PLT: platelets; MPV: mean platelet volume; PCT: plateletcrit; RDW: red blood cell distribution width; PDW: platelet distribution width.