Table 2.
Parameters | Control (honey) | Low dose (2.5 mg/kg b.w.) | Mid dose (25 mg/kg b.w.) | High dose (50 mg/kg b.w.) |
---|---|---|---|---|
Glucose (mg/dL) | 111.20 ± 21.07 | 90.20 ± 27.93 | 94.20 ± 29.65 | 102.10 ± 38.30 |
Blood urea (mg/dL) | 34.90 ± 8.97 | 46.60 ± 9.14* | 39.90 ± 8.99 | 29.80 ± 6.4 |
Creatinine (mg%) | 0.73 ± 0.24 | 0.990 ± 0.36* | 0.92 ± 0.36 | 0.62 ± 0.12 |
Cholesterol (mg/dL) | 112.70 ± 38.86 | 153.30 ± 45.32* | 110.70 ± 42.06 | 94.80 ± 17.88 |
TGL (mg/dL) | 89.00 ± 18.08 | 87.10 ± 29.77 | 75.80 ± 19.11 | 87.40 ± 25.20 |
Total protein (g%) | 8.32 ± 0.56 | 8.38 ± 0.64 | 10.24 ± 2.17 | 10.15 ± 3.67 |
Albumin (g%) | 2.79 ± 0.35 | 3.04 ± 0.42* | 2.35 ± 0.45 | 2.98 ± 0.43 |
S. bilirubin (mg/dL) | 0.710 ± 0.119 | 0.74 ± 0.06 | 0.630 ± 0.14 | 0.610 ± 0.21 |
SGOT (IU/L) | 168.00 ± 14.81 | 165.50 ± 19.092 | 167.80 ± 16.19 | 169.10 ± 12.76 |
SGPT (IU/L) | 62.00 ± 8.91 | 57.70 ± 14.855 | 49.40 ± 8.05 | 67.60 ± 41.21 |
Na+ (mEq/L) | 130.10 ± 5.56 | 132.20 ± 2.300 | 133.10 ± 1.66 | 133.10 ± 2.02 |
K+ (mEq/L) | 5.76 ± 2.43 | 6.26 ± 1.1909 | 5.590 ± 1.20 | 5.240 ± 0.72 |
Cl− (mEq/L) | 107.00 ± 1.41 | 106.30 ± 1.947 | 105.90 ± 1.79 | 105.90 ± 1.79 |
Comparison was made between vehicle control and test groups using the one-way ANOVA test followed by Dunnett's test. Values are mean ± SD for 10 rats in each group (P * < 0.05).
TGL: triglycerides, SGOT: serum glutamic oxaloacetic transaminase, SGPT: serum glutamic pyruvic transaminase, Na+: sodium, K+: potassium, and Cl−: chloride.