Table 2.

Elements and the statistical indices for multiple linear regression models which link the values of metabolic fluxes and the average AA property for the yeast Saccharomyces cerevisiae enzyme sequences, expressed according to the VARIMAX scales.

Model	Dependenta  variable	Parametersb	Regression coefficient (standardized value)	S.E.	t value	P value	R 2, % R adj. 2, %	VIFc
I	Metabolic flux (Teusink's model)	Constant	142.527	3.150	45.25	0.0000	94.46
							93.32
		P aveWV7	1749.250 (1.141)	80.843	21.64	0.0000		1.71
		P aveWV5	−1347.310 (−0.948)	86.853	−15.51	0.0000		2.29
		(P aveWV1)2	−1234.03 (−0.540)	124.491	−9.91	0.0000		1.82
		(P aveWV5)2	−11296.70 (−0.310)	1930.380	−5.85	0.0000		1.73
		(P aveWV2)2	−6350.430 (−0.289)	1137.530	−5.58	0.0000		1.64
		P aveWV6	202.670 (0.222)	48.639	4.17	0.0002		1.74
		P aveWV1	44.481 (0.125)	17.534	2.54	0.0159		1.50
II	Metabolic flux (Hynne's model)	Constant	70.629	3.394	20.81	0.0000	94.20
							92.91
		(P aveWV2)2	−0.780 (−0.638)	0.081	−9.65	0.0000		2.71
		P aveWV7	8.965 (1.028)	0.575	15.60	0.0000		2.70
		P aveWV1	−0.836 (−0.396)	0.112	−7.47	0.0000		1.74
		(P aveWV1)2	−0.083 (−0.610)	0.008	−10.11	0.0000		2.26
		(P aveWV5)2	−0.787 (−0.618)	0.076	−10.31	0.0000		2.23
		P aveWV5	−3.874 (−0.581)	0.383	−10.11	0.0000		2.05
		P aveWV6	2.683 (0.505)	0.311	8.63	0.0000		2.12
		(P aveWV3)2	−0.085 (−0.414)	0.014	−5.97	0.0000		2.99

^aRepresent the mean values of metabolic fluxes within the range of external glucose concentrations as specified in the “Material and Methods”.

^bElements of multiple linear regression which represent the average AA property, as specified in the Table 1, of the yeast Saccharomyces  cerevisiae enzyme sequences and the constant (intercept) of equation.

^cThe variance inflation factor which indicates the impact of collinearity between the independent variables [22].