Table 2.
Association of perinatal mortality with selected laboratory findings, treatment modalities, and outcome among women with hypertensive disorders of pregnancy, Ethiopia, 2008–2013.
Variables* | Total | Perinatal deaths (%) | Crude HR (95% CI) |
Adjusted**
HR (95% CI) |
---|---|---|---|---|
Hemoglobin level (gm/dL) | ||||
<10.0 | 158 | 36.1 | 1.0 (0.71–1.51) | |
10–11.9 | 255 | 26.7 | 0.7 (0.51–1.00) | |
≥12 | 602 | 32.7 | 1 | |
Platelet count in mm3 | ||||
<100 | 223 | 47.5 | 2.3 (1.66–3.31)† | 1.5 (0.83–2.85) |
≥100 | 792 | 27.3 | 1 | 1 |
Proteinuria (qualitative) | ||||
Insignificant | 266 | 27.1 | 1 | |
Significant | 749 | 30.4 | 1.2 (0.89–1.68) | |
Highest creatinine (gm/dL) | ||||
<1.0 | 494 | 26.3 | 1 | 1 |
1.0+ | 521 | 36.8 | 1.5 (1.05–2.03)¥ | 0.8 (0.51–1.39) |
Highest SGOT (IU/microl) | ||||
<2-fold raise | 689 | 24.5 | 1 | 1 |
≥2-fold raise | 326 | 46.9 | 2.9 (1.96–4.22)† | 2.3 (1.30–3.91)‡ |
Antihypertensive drug given | ||||
Yes | 811 | 32.8 | 1 | |
No | 204 | 27.5 | 0.8 (0.55–1.11) | |
Anticonvulsant drug given | ||||
MgSO4 | 641 | 30.6 | 1 | |
Diazepam | 374 | 33.7 | 1.1 (0.81–1.41) | |
Labor onset | ||||
Spontaneous | 331 | 26.3 | 2.3 (1.49–3.78)† | 0.7 (0.25–2.07) |
Induced | 504 | 41.1 | 4.9 (3.16–7.49)† | 1.6 (0.69–3.81) |
Direct C/S | 180 | 15.6 | 1 | 1 |
Mode of delivery | ||||
Vaginal | 625 | 41.1 | 4.5 (3.32–6.13)† | 5.3 (2.93–9.54)† |
Caesarean section | 485 | 13.4 | 1 | 1 |
Birth weight (kg) | ||||
<2.5 | 545 | 42.7 | 4.1 (3.02–5.45)† | 4.3 (2.56–7.23)† |
2.5+ | 565 | 15.7 | 1 | 1 |
Maternal outcome | ||||
Alive on discharge | 964 | 29.0 | 1 | 1 |
Dead | 51 | 82.3 | 7.1 (3.79–13.38)† | 12.8 (2.99–54.49)‡ |
¥ P < 0.05; ‡ P = 0.001; † P < 0.0001. *All variables describe the mother's condition except mode of delivery and birth weight. **Adjusted for platelet count, creatinine level, SGOT level, labor onset, mode of delivery, birth weight, and maternal outcome. C/S: Caesarean section. SGOT: serum glutamic oxaloacetic transaminase.