Table 4.
Results of fatty acid analysis with GC.
| Fatty acid | Before MPL (%) | After MPL (%) | Relative change of respective FA† | P |
|---|---|---|---|---|
| TG-fraction | ||||
| Myristic acid-C14:0 | 1.9 (0.5–5.6) | 2.2 (0.7–23.5) | +16% | <0.01 |
| Palmitic acid-C16:0 | 23.9 (14.7–35.7) | 23.2 (14.7–36.9) | −3% | <0.05 |
| Stearic acid-C18:0 | 3.7 (1.5–8) | 3.7 (1.9–7.2) | 0% | n.s. |
| Oleic acid-C18:1 | 34.1 (25.4–43.2) | 32 (23.1–45.3) | −6% | <0.01 |
| Linoleic acid (LA)-C18:2 | 27.6 (12.9–46.1) | 29.6 (15.8–47.9) | +7% | <0.01 |
| α-Linolenic acid (ALA)-C18:3 | 0.8 (0.1–9.6) | 1 (0–5) | +25% | <0.001 |
| Arachidonic acid (AA)∗-C20:4 | 4.1 (1.4–7.8) | 3.6 (0.5–8.4) | −12% | <0.01 |
| Eicosapentaenoic acid (EPA)-C20:5 | 0.6 (0.1–2.1) | 1 (0.2–3.4) | +67% | <0.001 |
| Docosahexaenoic acid (DHA)-C22:6 | 0.7 (0.2–2.1) | 1 (0.1–2.1) | +43% | <0.001 |
| ∑ of median values | 97.4 | 97.3 | ||
|
| ||||
| PL-fraction | ||||
| Myristic acid-C14:0 | 0.3 (0.1–0.7) | 0.4 (0.2–0.7) | +33% | <0.001 |
| Palmitic acid-C16:0 | 25.4 (15.9–30) | 24.9 (20.5–28.6) | −2% | <0.01 |
| Stearic acid-C18:0 | 11.7 (8.4–16.3) | 12.1 (8.4–15.8) | +3% | <0.001 |
| Oleic acid-C18:1 | 10.6 (5.6–14.2) | 10.7 (7.4–15.6) | 0% | n.s. |
| Linoleic acid (LA)-C18:2 | 17.4 (11.2–24.3) | 18.5 (8.3–23.9) | +6% | <0.01 |
| α-linolenic acid (ALA)-C18:3 | 0.2 (0–3.4) | 0.3 (0–0.9) | +50% | <0.001 |
| Arachidonic acid (AA)∗-C20:4 | 9.3 (3.2–14.8) | 8.5 (4.3–14.4) | −9% | <0.001 |
| Eicosapentaenoic acid (EPA)-C20:5 | 0.8 (0.2–3.4) | 1.4 (0.5–4.1) | +75% | <0.001 |
| Docosahexaenoic acid (DHA)-C22:6 | 3 (0.9–6.1) | 3.6 (1.5–5.9) | +20% | <0.001 |
| ∑ sum of median values | 78.7 | 75.4 | ||
∗Normal distribution.
†Change of FAs after MPL supplementation based on the median initial values.
Median relative values of each FA before and after MPL supplementation in the study population (n = 123). Since most of the data is not normally distributed, all values are given in median (min–max). Since C:17 lysophosphatidylcholine was used as internal standard, the results of C:17 are not shown in the table. C17 stays mostly in the PL fraction; therefore the values of the shown FAs (% of each FA) are not based on a 100%.