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. 2016 Jun 8;6:27435. doi: 10.1038/srep27435

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Copyright © 2016, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Five paired GC tumor tissues and adjacent non-tumor samples were collected. Total RNA was extracted and the expression of 33045 LncRNAs and 30215 mRNAs were determined by microarray. Analysis combining the data of lncRNAs and mRNAs, 6 lncRNAs have significantly altered expression, and in the same time, their neighboring genes (located near 300 kb upstream or downstream of lncRNA locus) level changed significantly. The vertical lines correspond to 1.5-fold up and down and the horizontal line represents a P-value of 0.05. The red point in the plot represents the differentially expressed LncRNAs with statistical significance.