Table 3. Plasma concentrations after the oral administration of rikkunshito at 1000 mg kg⁻¹ in rats.

Compound	Crude drug	Plasma concentration (ng/ mL)
		0.5 h	1 h	2 h
Nobiletin	Citri Unshiu Pericarpium	0.492 ± 0.190	0.127 ± 0.0306	0.0225 ± 0.000285
Tangeretin	Citri Unshiu Pericarpium	<0.020	<0.020	<0.020
Hesperetin	Citri Unshiu Pericarpium	0.192 ± 0.192	<0.100	<0.100
liquiritin apioside	Glycyrrhizae Radix	2.60 ± 0.699	1.73 ± 0.0985	0.913 ± 0.359
liquiritin	Glycyrrhizae Radix	2.84 ± 0.968	1.11 ± 0.0748	0.309 ± 0.213
Isoliquiritigenin	Glycyrrhizae Radix	0.392 ± 0.000667	0.267 ± 0.0361	0.174 ± 0.0347
Glycyrrhetic acid	Glycyrrhizae Radix	2.00 ± 1.68	0.396 ± 0.202	17.7 ± 16.6
Glycycoumarin	Glycyrrhizae Radix	<0.020	<0.020	<0.020
[8]-Shogaol	Zingiberis Rhizoma	<0.100	<0.100	<0.100