Table 2. Correlation coefficients between age and different PLCζ patterns in fertile controls, in infertile patients, and without separating these two groups (overall).
PLCζ localisation | Fertile Controls (n = 44) | Infertile Patients (n = 27) | Overall (n = 71) |
---|---|---|---|
% Sperm exhibiting PLCζ | 0.02 | 0.05 | 0.01 |
Total levels of PLCζ | 0.14 | −0.06 | −0.02 |
Localisation patterns (%) | |||
A | 0.13 | 0.02 | 0.09 |
PA | 0.19 | −0.08 | 0.08 |
E | −0.13 | −0.21 | −0.15 |
A + PA | 0.17 | 0.11 | 0.14 |
A+ E | −0.04 | 0.01 | −0.04 |
PA+ E | 0.10 | −0.06 | 0.03 |
A + PA +E | 0.05 | 0.05 | 0.02 |
None | −0.14 | 0.32 | 0.07 |
No significant correlations were observed in any of the cases evaluated. [Specific localisation patterns of PLCζ are referred to as: A = acrosomal; E = equatorial; None = absence of PLCζ; PA = post-acrosomal. ‘None’ refers to sperm that were completely devoid of PLCζ].