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. 2016 Jun 8;6:27644. doi: 10.1038/srep27644

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Copyright © 2016, Macmillan Publishers Limited

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Genetic variance in HRS based on SNP block ranking derived from GIANT summary association statistics. Three methods were tested to rank SNP blocks: LARGV (red), LD Score (blue) and multi-SNP locus-association (green). The median SNP block size was 250 Kb (i.e. 85–95 SNPs). Genetic variance was calculated in HRS using variance component models for BMI (a) and height (b).