Table 2.
Association between Type 2 Diabetes Mellitus and retinal measurements∗.
| Retinal variable | Model 1 β (95% CI) |
Model 2 β (95% CI) |
Model 3 β (95% CI) |
|---|---|---|---|
| Arteriolar measures | |||
| Length, pixels | 14.38 (−36.27 to 65.04) | 13.01 (−42.00 to 68.01) | 31.15 (−37.76 to 94.06) |
| Diameter, pixels | 0.48 (0.05 to 0.91)† | 0.34 (−0.13 to 0.80) | 0.01 (−0.52 to 0.54) |
| Length/diameter ratio | 0.08 (−2.11 to 2.26) | 0.12 (−2.24 to 2.49) | 1.24 (−1.46 to 3.95) |
| Simple tortuosity | 0.007 (−0.001 to 0.02) | 0.006 (−0.003 to 0.01) | 0.006 (−0.003 to 0.02) |
| Internal angle (°) | 2.89 (−0.34 to 6.12) | 2.83 (−0.66 to 6.33) | 2.63 (−1.50 to 6.76) |
| Optimality ratio | 0.01 (0.001 to 0.02)† | 0.01 (−0.01 to 0.02) | 0.004 (−0.01 to 0.02) |
|
| |||
| Venular measures | |||
| Length, pixels | 3.87 (−31.40 to 39.14) | 21.30 (−16.43 to 50.02) | 8.30 (−35.99 to 52.59) |
| Diameter, pixels | 0.08 (−0.61 to 0.77) | −0.21 (−0.95 to 0.54) | −0.45 (−1.32 to 0.43) |
| Length/diameter ratio | 0.18 (−1.12 to 1.47) | 0.95 (−0.44 to 2.33) | 0.65 (−0.98 to 2.27) |
| Simple tortuosity | 0.001 (−0.001 to 0.003) | 0.002 (−0.001 to 0.004) | 0.001 (−0.002 to 0.004) |
|
| |||
| Retinopathy | |||
| Any retinopathy (odds ratio) | 1.00 (0.68 to 1.47) | 1.47 (0.96 to 2.26) | 1.41 (0.85 to 2.32) |
∗Including nonsymmetrical second-order vessels for all bifurcations.
Model 1 unadjusted.
Model 2 adjusted for age and sex.
Model 3 adjusted for age, sex, and vascular risk factors (history of smoking, hypertension, systolic and diastolic blood pressure, BMI and history of stroke, ischemic heart disease, and hyperlipidaemia).
† p value < 0.05.