Table 3.
Frequency of Risk Factors Identified at Baseline among Women with Previous and Incident* Fractures (Rates per 1000 Women)
| Risk Factor | Previous Fracture | Incident Fracture (within 2 Years of Basline) | ||||||
|---|---|---|---|---|---|---|---|---|
| Group 1: Obese (n = 2274) | Group 2: Nonobese (n = 7401) | Group 3: Underweight (n = 220) | P Value† | Group 1: Obese (n = 633) | Group 2: Nonobese (n = 2170) | Group 3: Underweight (n = 53) | P Value† | |
| Previous fracture | 416 | 390 | 566 | 2 vs 3 | ||||
| Maternal hip fracture | 156 | 164 | 162 | 141 | 177 | 159 | ||
| Current estrogen use | 55.9 | 73.6 | 77.6 | 1 vs 2 | 57.1 | 73.4 | 94.3 | |
| Early menopause | 194 | 127 | 128 | 1 vs 2 | 200 | 139 | 98 | 1 vs 2 |
| Current cortisone use | 49.3 | 38.2 | 51.2 | 48.2 | 49.6 | 19.2 | ||
| Weight loss ≥10 lb | 113 | 103 | 207 | 1 vs 3, 2 vs 3 | 132 | 117 | 208 | |
| Current smoker | 56.6 | 79.6 | 152 | 1 vs 3, 2 vs 3 | 86.3 | 92.3 | 173 | |
| Alcohol >20 units/week | 1.3 | 5.2 | 0.0 | 1 vs 2 | 3.2 | 8.3 | 0.0 | |
| Arms assist | 605 | 359 | 347 | 1 vs 2, 1 vs 3 | 595 | 348 | 327 | 1 vs 2, 1 vs 3 |
| Fair/poor general health | 342 | 240 | 347 | 1 vs 2, 2 vs 3 | 345 | 257 | 321 | 1 vs 2 |
| Falls | ||||||||
| 1 in past 2 years | 270 | 265 | 298 | 256 | 259 | 358 | ||
| ≥ 2 in past 2 years | 242 | 187 | 234 | 1 vs 2 | 308 | 211 | 264 | 1 vs 2 |
Incident fracture is defined as a fracture of at least one of the following bones: clavicle, upper arm, wrist, spine, rib, hip, pelvis, ankle, upper leg, lower leg, hand, foot, elbow, knee, or shoulder.
We performed pairwise comparisons among the 3 groups, and report any results where Fisher’s exact test P ≤.017 (for example. 1 vs 2 means the difference between group 1 [obese] and group 2 [nonobese] is statisticallv significant at alpha = .017 level).