Table 3.
Mortality by study period and type of care pathways with main characteristics (type of Plasmodium and severity) (Period 1: 2000–2003, Period 2: 2004–2008, Period 3: 2009–2013)
| Period 1 | Period 2 | Period 3 | p value | Period 2 vs Period 1 | Period 3 vs Period 1 | |
|---|---|---|---|---|---|---|
| n (%) | n (%) | n (%) | Difference (CI 95 %)) | Difference (CI 95 %) | ||
| Adultsa | n = 6482 | n = 5514 | n = 4989 | |||
| Overall mortality | 24 (0.37) | 16 (0.29) | 14 (0.28) | 0.35 | −0.08 % (−0.3; 0.13) | −0.09 % (−0.32; 0.12) |
| P. falciparum | 22 (0.34) | 16 (0.29) | 14 (0.28) | 0.50 | ||
| Severity–French criteria | 19 (0.29) | 11 (0.2) | 14 (0.28) | 0.50 | ||
| Severity–clinical classification | 21 (0.32) | 15 (0.27) | 14 (0.28) | 0.50 | ||
| Medicine ward | 2 (0.09) | 1 (0.06) | 2 (0.15) | 0.87 | ||
| ICU | 14 (8.5) | 10 (5.52) | 12 (3.96) | 0.09 | ||
| Ambulatory care | 1 (0.05) | 0 (0) | 0 (0) | 0.13 | ||
| Childrenb | n = 2066 | n = 1308 | n = 895 | |||
| Overall mortality | 2 (0.1) | 0 (0) | 1 (0.11) | 0.52 | −0.1 % (−0.47; 0.1) | (0.01 % (−0.5; 0.29) |
| P. falciparum | 2 (0.1) | 0 (0) | 0 (0) | 0.33 | ||
| Severity–French criteria | 0 (0) | 0 (0) | 1 (0.11) | 0.33 | ||
| Severity–clinical classification | 1 (0.5) | 0 (0) | 1 (1.1) | 0.33 | ||
| Medicine ward | 0 (0) | 0 (0) | 0 (0) | |||
| ICU | 2 (14.9) | 0 (0) | 0 (0) | 0.006 | ||
| Ambulatory care | 0 (0) | 0 (0) | 0 (0) |
Data are number (%)
aFor five dead adults, the type of pathway was missing. Among hospitalized adults, the type of hospitalization was missing for seven adults
bThe third dead child was hospitalized but the type of hospitalization was missing