Table 3.
Top ten MeCP2-enriched promoters and genes identified by ChIP-seq in the DRG from SNI model compared to sham control
| Nearest refseq | Gene name | Gene description | Tag count | p value | |
|---|---|---|---|---|---|
| Sham | SNI | ||||
| Promoters with enriched MeCP2 binding | |||||
| NM_021478 | Tulp1 | Tubby like protein 1 | 0 | 30 | 2.85E−06 |
| NM_027398 | Kcnip1 | Kv channel-interacting protein 1 | 0 | 19 | 0.000195 |
| NM_170757 | Ccdc186 | Coiled-coil domain containing 186 | 0 | 16 | 0.000629 |
| NM_001034898 | Ms4a15 | Membrane-spanning 4-domains, subfamily A, member 15 | 0 | 25 | 1.92E−05 |
| NR_033168 | Snora28 | Small nucleolar RNA, H/ACA box 28 | 0 | 26 | 1.31E−05 |
| NM_001113379 | Lrrc32 | Leucine rich repeat containing 32 | 0 | 25 | 1.92E−05 |
| NM_011305 | Rxra | Retinoid X receptor alpha | 0 | 15 | 0.000932 |
| NM_018820 | Sertad1 | SERTA domain containing 1 | 0 | 17 | 0.000425 |
| NM_001011525 | Olfr1415 | Olfactory receptor 1415 | 0 | 16 | 0.000629 |
| NM_133759 | Zbtb3 | Zinc finger and BTB domain containing 3 | 0 | 25 | 1.92E−05 |
| Gene bodies with enriched MeCP2 binding | |||||
| NM_001001807 | Olfr279 | Olfactory receptor 279 | 0 | 21 | 8.97E−05 |
| NM_011540 | Tcap | Titin-cap | 0 | 16 | 0.000629 |
| NM_011971 | Psmb3 | Proteasome (prosome, macropain) subunit, beta type 3 | 0 | 19 | 0.000195 |
| NM_198414 | Paqr9 | Progestin and adipoQ receptor family member IX | 0 | 20 | 0.000132 |
| NM_133668 | Slc25a3 | Solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3 | 0 | 15 | 0.000932 |
| NM_001160356 | Uqcc3 | Ubiquinol-cytochrome c reductase complex assembly factor 3 | 0 | 15 | 0.000932 |
| NM_001190356 | Gm4832 | Predicted gene 4832 | 0 | 15 | 0.000932 |
| NM_133759 | Zbtb3 | Zinc finger and BTB domain containing 3 | 0 | 25 | 1.92E−05 |
| NM_009296 | Supt4a | Suppressor of Ty 4A | 0 | 20 | 0.000132 |
| NM_009756 | Bmp10 | Bone morphogenetic protein 10 | 0 | 18 | 0.000288 |