Table 5.
Celiac disease risk in relation to maternal infections during early life in all children
| Descriptive | ||||||
|---|---|---|---|---|---|---|
| Exposures | CD Cases | Not CD cases | Bivariate analyses | Multivariable analyses | ||
| N (%) | N (%) | OR (95 % CI) | P-value | OR (95 % CI) | P-value | |
| Urinary tract infections | ||||||
| No | 5 700 (86) | 1 667 663 (88) | 1.0 | 1.0 | ||
| Yes | 896 (14) | 237 935 (13) | 1.1 (1.0–1.2) | 0.007 | 1.2 (1.1–1.2)a | <0.001 |
| Other maternal infections | ||||||
| No | 6 561 (99) | 1 893 642 (99) | 1.0 | 1.0 | ||
| Yes | 35 (0.5) | 11 956 (0.6) | 0.8 (0.6–1.2) | 0.32 | 0.9 (0.7–1.4)a | 0.80 |
| urinary tract infections, <35years, Low income | ||||||
| Yes | 689 (63) | 136 479 (48) | 1.0 | 1.0 | ||
| No | 343 (37) | 150 895 (53) | 0.5 (0.5–0.6) | <0.001 | 0.5 (0.4–0.6)b | <0.001 |
aAdjusted for maternal age, disposable income, body mass index, parity, and duration of pregnancy, infant birth weight, sex, and Apgar score and urinary tract infections
bAdjusted for body mass index, parity, pregnancy duration, and premature rupture of the membrane, infant birth weight, sex, Apgar score and other maternal infections