Table 3.
Univariate analysis of all patients (n = 146) for primary and secondary endpoint
| Variable | Primary endpoint | Secondary endpoint | ||||
|---|---|---|---|---|---|---|
| HR | 95%CI | p-value | HR | 95%CI | p-value | |
| Gender | 0.91 | 0.34–2.43 | 0.85 | 0.77 | 0.35–1.70 | 0.52 |
| Age (yrs) | 1.02 | 0.99–1.05 | 0.15 | 1.03 | 1.00–1.05 | 0.04 |
| NYHA class | 1.13 | 0.60–2.11 | 0.70 | 1.32 | 0.78–2.26 | 0.31 |
| LVEF (%) | 0.90 | 0.86–0.94 | <0.0001 | 0.92 | 0.89–0.95 | <0.0001 |
| LVEDV/BSA (ml/m2) | 1.02 | 1.01–1.02 | <0.0001 | 1.01 | 1.01–1.02 | <0.0001 |
| LGE present | 3.43 | 1.42–8.27 | 0.006 | 2.00 | 1.01–3.95 | 0.048 |
| LVGFI (%) | 0.86 | 0.81–0.91 | <0.0001 | 0.89 | 0.85–0.93 | <0.0001 |
| LAS (%) | 1.46 | 1.25–1.71 | <0.0001 | 1.41 | 1.23–1.60 | <0.0001 |
Univariate analysis revealed that LVEF, LVEDV/BSA, LGE present, LVGFI and LAS were significant paramters regarding the primary endpoint, while age, LVEF, LVEDV/BSA, LGE present, LVGFI and LAS were significantly associated with the secondary endpoint (significant p-values in bold letters)