Table 3.
The scores for tissue edema, collagen production and epidermis migration.
| Groups | Edema score | Collagen score | Epidermis thickness |
|---|---|---|---|
| Day 3 | |||
| Negative control | ++++ | − | − |
| Positive control | ++++ | − | − |
| LD (MCO 1%) | +++ | + | − |
| MD (MCO 3%) | ++ | + | − |
| HD (MCO 6%) | ++ | ++ | + |
| Day 7 | |||
| Negative control | ++++ | + | − |
| Positive control | +++ | + | − |
| LD (MCO 1%) | +++ | ++ | + |
| MD (MCO 3%) | ++ | +++ | + |
| HD (MCO 6%) | + | +++ | ++ |
| Day 14 | |||
| Negative control | +++ | ++ | + |
| Positive control | +++ | ++ | + |
| LD (MCO 1%) | ++ | +++ | + |
| MD (MCO 3%) | + | +++ | ++ |
| HD (MCO 6%) | − | +++ | ++++ |
| Day 21 | |||
| Negative control | ++ | +++ | +++ |
| Positive control | ++ | +++ | +++ |
| LD (MCO 1%) | + | +++ | ++++ |
| MD (MCO 3%) | − | ++++ | ++++ |
| HD (MCO 6%) | − | ++++ | ++++ |
Note: The Masson-trichrome staining was scored into ++++: Intensive; +++: Moderate; ++: Mild; +: Faint; −: Negative.